Amyloid precursor protein (APP) is a type I transmembrane glycoprotein that undergoes complex routing through the secretory and endocytic pathways of neurons and non-neuronal cells. Proteolytic ...
(A, B) ALP staining and activity detection were performed after treating cells with APPswe or BMP2 for 5 days or 7 days. (C, D) ARS staining and semiquantitative analysis were used to detect calcium ...
Watching the Alzheimer’s research world from the outside over the past two years has felt like a car ride over an unpaved mountain road without a seatbelt. In 2021, the US Food and Drug Administration ...