The cGAS-STING pathway is emerging as a key driver of chronic neuroinflammation through its effects on glial activation, ...

Crownlands, Inc., a company scaling the collection of living human neurons to generate molecular data for AI-driven drug discovery and clinical trial modeling, today announced the public release of a ...

Researchers found that KAT7 promotes CMPK2-driven mitochondrial DNA release in microglia, activating inflammatory cGAS-STING ...

BUFFALO, N.Y. — A hallmark of Parkinson’s disease is the buildup of Lewy bodies — misfolded clumps of the protein known as alpha-synuclein. Long before Lewy bodies form, alpha-synuclein can interfere ...

Within the human brain, movement is coordinated by a brain region called the striatum, which sends instructions to motor neurons in the brain. Those instructions are conveyed by two pathways, one that ...