Skeletal stem cells (SSCs) are essential for bone development, homeostasis, and repair. Recent studies have identified distinct SSC populations in long bones, craniofacial bones, and spine. Techniques ...

Growth plates are areas of cartilage found at the ends of long bones. They play a role in the bone growth of children and teens. An injury to a growth plate can affect the development of a bone. While ...

Scientists have identified a protein that blocks the activity of bone-forming cells (osteoblasts) by stopping them from maturing during the journey to sites of bone formation. Endothelial cell's job ...

In vertebrates, the skeleton of different regions of the body arises from different precursor cells. Researchers have now discovered that these skeletal cells do not just differ in their developmental ...

In the elderly, a multitude of factors contribute to diminished bone regeneration capabilities, including a reduction in the self-renewal and differentiation abilities of mesenchymal stem cells, an ...

Skeletal conditions such as developmental dysplasia of the hip (DDH), osteoporosis, and osteoarthritis affect millions worldwide, often causing chronic pain and disability. These disorders stem from ...